Feline hyperthyroidism is the most common endocrine disease in older cats; welfare outcomes depend on selecting the optimal treatment for individual circumstances.
Untreated feline hyperthyroidism causes progressive deterioration through weight loss, muscle wasting, cardiac disease and hypertension. The welfare significance increases as the disease progresses. Treatment dramatically improves quality of life for affected cats. Treatment selection must consider the cat's temperament, owner circumstances and concurrent health conditions. Radioactive iodine provides the most durable welfare outcome but requires a period of hospitalisation. The unmasking of renal disease after treatment requires careful management to optimise overall welfare.