Rabbits are among the most commonly used animals in laboratory research, particularly for safety testing, and face specific welfare challenges including social isolation and fear responses.
The welfare needs of laboratory rabbits - including social contact, space for movement, hiding opportunities, and minimal handling stress - are often poorly met in traditional research settings. The 3Rs framework (Replacement, Reduction, Refinement) provides a pathway to improved rabbit welfare, with refinements like positive reinforcement training and social housing demonstrating both welfare and scientific benefits.