Companion Animals

Companion Cat Polycystic Kidney Disease Screening

Polycystic kidney disease (PKD) is common in Persian-type cats and genetic testing enables welfare-focused breeding decisions.

Key Facts

PKD affects up to 40% of Persian cats in some populations without selective breeding
The condition is caused by a dominant gene mutation identifiable through DNA testing
Affected cats develop progressive kidney cysts causing renal failure typically in middle age
Breeding only from PKD-negative tested cats can eliminate the disease from breeding lines

Welfare Considerations

PKD causes progressive kidney disease and renal failure causing chronic discomfort and ultimately uraemia. The disease is genetically preventable through responsible breeding with tested cats. Continuing to breed untested Persians and related breeds perpetuates preventable welfare compromise.

What You Can Do

Only purchase Persian cats from breeders who genetic test for PKD
Advocate for mandatory PKD testing in Persian cat breed standards
Support breed reform efforts prioritising health testing in cat breeding