Non-human primates used in biomedical research face significant welfare challenges, with the 3Rs framework driving important improvements in housing and procedures.
Non-human primates in research face welfare challenges from housing, procedures, and social disruption. Historically, single housing was common for procedural convenience, causing severe psychological harm to highly social species. Mandatory social housing requirements represent a significant welfare improvement. Further progress requires investment in positive reinforcement training that allows voluntary participation in procedures, reducing both animal stress and human injury risk.