Laboratory mice and rats are highly social animals that suffer significantly when housed alone, yet single housing remains common in research facilities for convenience.
Laboratory rodent single housing is a pervasive welfare problem maintained by outdated conventions rather than scientific necessity. Research demonstrates that isolated mice and rats show physiological and behavioral abnormalities that both indicate welfare harm and compromise experimental validity. The welfare and scientific cases for social housing align perfectly, yet cultural inertia in research institutions perpetuates unnecessary isolation. Regulatory requirements for social housing with justified exceptions represent the most effective intervention.