Companion Animals

Dog Canine Cognitive Dysfunction Pharmacology

Pharmacological treatment of canine cognitive dysfunction syndrome complements environmental management and may slow progression in affected dogs.

Key Facts

Selegiline (Anipryl) is the only licensed treatment for canine cognitive dysfunction in the UK
Propentofylline improves blood flow to the brain and has supporting evidence
Melatonin may improve sleep-wake cycle disruption in affected dogs
Dietary supplements including phosphatidylserine and antioxidants have supporting evidence
Regular reassessment allows monitoring of disease progression and treatment response

Welfare Considerations

Dogs with cognitive dysfunction experience progressive confusion, altered sleep, and reduced quality of life. Pharmacological treatment may slow progression and improve specific symptoms including sleep disruption and anxiety. Combined with environmental enrichment and management, medication provides a comprehensive approach to maximising welfare during cognitive decline.

What You Can Do

Discuss pharmacological treatment options with your vet for dogs with cognitive decline
Maintain a sleep diary to assess treatment response for sleep disturbance
Combine medication with environmental enrichment and routine management