Mink are used as an animal model for influenza and other respiratory viruses, raising welfare questions about housing and procedures for an animal with strong swimming and ranging drives.
Mink used in research face identical housing welfare challenges to mink on fur farms: cage confinement that prevents swimming and ranging, lack of environmental complexity, and the chronic stress of an active predatory species unable to express natural behavior. Stereotypic behaviors affect the majority of caged mink and indicate significant psychological distress. The welfare cost of mink research needs to be weighed against the research benefits, with attention to the 3Rs principle of refinement — improving housing and enrichment to minimize the welfare impact on individual animals used.