Cats used in biomedical research face welfare challenges, and the 3Rs framework - Replacement, Reduction, and Refinement - provides a path to improved outcomes.
Laboratory cats experience confinement, handling stress, and research procedures that cause discomfort. While animal research has regulatory oversight, cats' social complexity and sensitivity make welfare particularly important. Applying the 3Rs rigorously - replacing cats with alternatives where possible, reducing numbers, and refining procedures to minimise suffering - is the framework for progress.