Wildlife-to-human disease transmission events harm both human health and animal welfare, often triggering mass culling of wild and farmed animal populations.
Zoonotic disease management creates welfare harms for animals at multiple points: wildlife in live markets experience confinement stress; farmed animal populations are mass culled when disease spillover is detected; and wild animals may be persecuted when identified as reservoir hosts. More humane approaches include disease surveillance that avoids mass culling, targeted testing rather than blanket eradication, and vaccination programs where available.