Chytridiomycosis caused by the Batrachochytrium dendrobatidis fungus has caused the most significant vertebrate disease-driven biodiversity loss in history.
Chytridiomycosis causes a slow death from electrolyte failure. Affected amphibians show lethargy, abnormal posture, and loss of righting reflex before death. The scale of suffering across millions of individual animals globally is enormous. Biosecurity to prevent spread and probiotic treatments to protect vulnerable populations represent the most practical welfare interventions.