Advanced management of feline gingivostomatitis includes post-extraction immune modulation and monitoring for the minority of cases not resolved by extraction.
For the 20-40% of gingivostomatitis cats not resolved by extraction, long-term management requires ongoing immunosuppression with its associated welfare trade-offs. Cyclosporine provides better disease control than steroids with fewer long-term side effects. Emerging treatments including stem cell therapy offer hope for refractory cases. Each treatment advance represents potential relief for cats suffering from this severely painful condition.