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Cryptococcosis in Cats: Fungal Infection Welfare Guide

Cryptococcosis is a serious fungal infection in cats primarily affecting the nose and nervous system. This guide covers welfare impacts and treatment.

Key Facts

Cryptococcosis is caused by Cryptococcus neoformans or C. gattii fungi from the environment
The nasal cavity and sinuses are most commonly affected in cats
Signs include swelling over the nose, nasal discharge, sneezing, and neurological signs
CNS invasion causes severe neurological disease with poor prognosis
Long-term antifungal therapy (fluconazole or itraconazole) is required
Australia, USA, and tropical areas have highest disease prevalence

Welfare Considerations and Management

Welfare-centred management of cryptococcosis requires prolonged antifungal therapy and regular monitoring. Fluconazole is the most commonly used first-line treatment with good CNS penetration. Treatment duration is typically 6-12 months or longer with response confirmed by antigen testing. Surgical debulking of large nasal masses improves treatment access. CNS disease has a poor prognosis despite treatment. Monitoring includes regular antigen titre measurement and clinical assessment.

What You Can Do

Pursue antifungal treatment promptly — early treatment before CNS involvement gives best prognosis
Administer antifungal medications consistently for the full recommended duration
Monitor response with regular cryptococcal antigen titres
Seek specialist referral for cats with neurological signs or poor treatment response