Chronic kidney disease affects the majority of elderly cats and requires long-term welfare management balancing quality of life with treatment burden.
Cats with advanced CKD experience nausea from uraemia, reduced appetite, weight loss and lethargy. Fluid therapy reduces uraemic toxin concentrations and dramatically improves short-term quality of life, but requires home administration by owners that some cats find stressful. Dietary management reduces progression speed. Anti-nausea medication improves appetite and quality of life in cats with nausea. Palliative management of CKD with welfare as the primary goal produces better outcomes than aggressive interventions focused only on biochemical markers.