Companion Animals

Cryptococcosis in Cats: Welfare and Antifungal Treatment

Managing systemic fungal infection in cats to resolve neurological and respiratory welfare compromise.

Key Facts

Cryptococcus neoformans causes systemic fungal infection affecting nose, skin, and brain
Cats are the most commonly affected domestic species — via inhalation of spores
Nasal mass, sneezing, and neurological signs are classic presentations
Long-term antifungal treatment with fluconazole or itraconazole is required — often 6-12 months

Welfare Considerations

Cryptococcosis causes significant welfare compromise through nasal obstruction, neurological signs, and systemic illness. Welfare management requires accurate diagnosis through antigen testing and culture, prompt initiation of appropriate antifungal therapy, and long-term treatment monitoring. Neurological cryptococcosis has a guarded prognosis but many cats with nasal disease achieve full recovery with treatment.

What You Can Do

Investigate chronic nasal discharge or swelling in cats with appropriate diagnostics including antigen testing
Commit to the full treatment course — premature cessation leads to relapse
Monitor regularly during treatment — renal and hepatic side effects require surveillance