Megacolon causes severe, chronic constipation in cats from colonic nerve dysfunction. Medical management and surgical subtotal colectomy restore welfare for affected cats.
Megacolon causes severe discomfort and abdominal pain from accumulated faecal material that cannot be passed. Obstipation episodes require repeated anaesthesia for manual evacuation, causing stress and anaesthetic risk. Medical management with lactulose, dietary change, and motility drugs helps mild cases but typically cannot control progressive disease. Subtotal colectomy removes the dysfunctional colon segment and most cats achieve good-to-excellent quality of life with mild diarrhoea for weeks before forming soft normal stools.