Companion Animals

Plasma Cell Pododermatitis in Cats: Welfare and Treatment

Managing pillow foot (plasma cell pododermatitis) to relieve pain and restore mobility.

Key Facts

Plasma cell pododermatitis causes swelling and softening of paw pads
Immune-mediated condition — plasma cells infiltrate the pad tissue
Soft, spongy pads may ulcerate causing pain and difficulty walking
Many cases respond to doxycycline or immunosuppressive treatment

Welfare Considerations

Plasma cell pododermatitis causes chronic paw pain that impairs mobility and normal behaviour. Welfare-focused management identifies the condition early before ulceration occurs and initiates treatment promptly. Doxycycline is often effective in mild cases — severe or unresponsive cases may require surgical pad debridement. Long-term monitoring for recurrence is needed.

What You Can Do

Inspect your cat's paw pads regularly for softening, swelling, or discolouration
Seek vet assessment for any cat showing reluctance to walk or paw licking
Follow through with full treatment course — relapse is common without complete resolution