Perianal fistulae cause extremely painful draining tracts around the anus in dogs, particularly German shepherds. Modern immunosuppressive treatment achieves remission in most cases.
Perianal fistulae cause extreme pain that profoundly affects quality of life. Dogs may refuse to defecate due to the pain of passing faeces, leading to constipation and further discomfort. The chronic draining tracts become infected and inflamed. Cyclosporin A provides remission by suppressing the autoimmune process driving tissue destruction. Treatment requires 16-20 weeks of consistent administration. Regular monitoring with dose adjustment achieves lasting remission. Early diagnosis and treatment prevents the progressive tissue destruction that makes severe cases harder to manage.